Suicide is a major mental health concern that devastates lives and causes unimaginable pain. In fact, in 2020, suicide was the 12th leading cause of death in the U.S., with nearly 46,000 people dying this way. What can we as mental health professionals do to help conquer this issue? We need to understand better the clinical reasons behind the decision to commit suicide. Suicide doesn’t have a clear etiology, and many factors influence whether a person will become suicidal, including their neurobiology, personal and family history, stressful events they may have experienced, and sociocultural environment . However, suicide can be viewed as “a behavior motivated by the desire to escape from unbearable psychological pain .” Psychological factors, including personality and emotions, also contribute . Interestingly, decision-making impairment seems to be an increasingly important influence. It's critical that we promote within our own organizations and communities the fact that suicide is preventable. Years ago, researchers found that almost half of people who commit suicide visit a primary care doctor within 1 month of death but don’t admit to or consult with the doctor about any suicide intent or ideation. Many people who commit suicide are social and active—they are struggling under the surface and do not seek help. September 5–11 is National Suicide Prevention Week. This week, the Substance Abuse and Mental Health Services Administration (SAMHSA) encourages everyone to put the topic of suicide prevention top of mind. Make sure your patients, clients, and students know about suicide risk factors, warning signs , and what they can do to prevent suicide. And be sure to emphasize the new three-digit phone number for the Suicide Prevention Lifeline—made active across the country in July: 988. For more information about what you can do this week to promote suicide prevention, visit this site . If you are treating patients and need more information about tools you can use for assessing suicide intent, visit our mental health resources page. If you or someone you know is considering suicide, you are not alone. Dial 988 to reach the Suicide Prevention Lifeline for immediate help, 24/7.